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. 2018 Jun 22;20:62. doi: 10.1186/s13058-018-1003-1

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — CD8, FOXP3, and CD8/FOXP3 ratio in skin versus other metastasis sites. Boxplots comparing CD8, FOXP3, and CD8/FOXP3 ratio in skin versus other metastasis sites in all patients and in TN and HER2+ cohorts separately (a). Pictures showing a skin metastasis with high TILs and low CD8/FOXP3 ratio and a liver metastasis with low TILs and high CD8/FOXP3 ratio (b). HER2 human epidermal growth factor receptor-2, TILs tumor-infiltrating lymphocytes, TN triple negative.