Table 3.

OS univariate and multivariate analysis of immune parameters evaluated on metastasis biopsies of triple-negative breast cancer

			Univariate		Multivariate
		Median OSmonths (95%CI)	HR (95%CI)	p	HR (95%CI)
TILs	Low ≤10%	11.8 (4.1–19.5)	ref	0.012	ref
	High > 10%	62.9 (52.3–73.5)	0.29 (0.11–0.76)		0.06 (0.01–0.29)
CD8/FOXP3 ratio	1st tertile	8.0 (0.0–17.1)	ref	0.020	ref
	2nd tertile	13.2 (0.0–28.3)	0.59 (0.22–1.58)		0.17 (0.05–0.59)
	3rd tertile	54.0 (32.4–75.7)	0.20 (0.06–0.67)		0.03 (0.004–0.15)

Abbreviations: OS overall survival, HR hazard ratio, p p value, TILs tumor-infiltrating lymphocytes

Significant p values in bold