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. 2018 Jun 22;19:36. doi: 10.1186/s12868-018-0436-x

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© The Author(s) 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Thyroxine levels (μg/dl) in responders (gray bars) and nonresponders (white bars) to donepezil therapy at baseline and 24–26 weeks after treatment. The responders (n = 13) had with a higher baseline level of T₄ compared with the non-responders (n = 8) (t(19) = 2.29, p = .033) and a significant reduction in T₄ level after 24–26 weeks of donepezil treatment (F(1,12) = 13.13, p = .003)