Table 1.
Demographic and clinical characteristics between in patients with Alzheimer disease (AD) and controls
| Variables (mean ± SD) | Controls | AD patients | t(39) or χ2 (1) values | p value |
|---|---|---|---|---|
| n (M/F) | 20 (9/11) | 21 (7/14) | 0.59 | .530 |
| Age (year) | 77.5 ± 4.4 | 78.5 ± 5.7 | − 0.67 | .504 |
| Years of education | 6.6 ± 4.4 | 5.0 ± 5.1 | 1.07 | .293 |
| MMSE scores | 27.5 ± 1.9 | 16.1 ± 5.4 | 8.93 | < .001 |
| Cortisol (μg/dl) | 7.8 ± 3.7 | 10.2 ± 2.9 | − 2.34 | .025 |
| Thyrotropin (mIU/l) | 1.4 ± 0.7 | 1.4 ± 0.9 | − 0.01 | .996 |
| Total T3 (ng/dl) | 94.8 ± 10.2 | 85.5 ± 8.6 | 3.18 | .003 |
| Free T3 (pg/ml) | 2.5 ± 0.4 | 2.3 ± 0.3 | 2.56 | .015 |
| Total T4 (μg/dl) | 6.3 ± 1.1 | 6.4 ± 1.0 | − 0.33 | .747 |
| Free T4 (ng/dl) | 1.0 ± 0.1 | 1.0 ± 0.1 | − 0.23 | .818 |
MMSE Mini–Mental State Examination