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. 2018 Jun 15;12:404. doi: 10.3389/fnins.2018.00404

FIGURE 1.

FIGURE 1

Illustration of a disolvated H+. In solution H+ is solvated (Eigen ion) usually disolvated by 2 H2O (Zundel ion). The α-C bound O-atom of monocarbonic acids, such as lactic acid and pyruvic acid, intra-molecularly disolvate the H+. The monocarbonic acids share the common characteristic of a partially positively charged (δ+) α-C atom to allow nucleophile substitution. Similarly, 1,3-bisphosphoglycerate uses O atoms to disolvate two protons.