Table 2.

Acute Mountain Sickness, Oxygen Saturation, Actual Dietary Intakes, and Meal Acceptability Measured During Appetite Testing Days Conducted at Sea Level and While Living at High Altitude (4300 m)

	Standard protein (n = 8)			Higher protein (n = 9)
	SL day 12	HA day 1	HA day 18	SL day 12	HA day 1	HA day 18
AMS,%n1,2	0	50	12	0	78	44
Nausea,%n1,3	0	37	25	0	44	44
O2 saturation,%4	96.6 ± 1.1a	83.0 ± 1.4b	87.0 ± 1.9c	97.1 ± 1.1a	79.0 ± 3.6b*	87.2 ± 1.9c
Energy intake, kcal/d4	1981 ± 185	2019 ± 193	1966 ± 243	1966 ± 274a	1775 ± 387b	1968 ± 267a
Protein intake, g/d5	93 ± 15	93 ± 14	91 ± 16	166 ± 26	148 ± 37	163 ± 26
Carbohydrate intake, g/d4	214 ± 23	219 ± 23	211 ± 30	215 ± 32a	199 ± 34b	216 ± 32a
Fat intake, g/d5	90 ± 7	92 ± 7	90 ± 9	55 ± 9	48 ± 15	56 ± 9
Meal acceptability6,7	7 ± 2	6 ± 2	5 ± 3	7 ± 2	6 ± 2	5 ± 3

Values are%n or mean ± SD.

¹Generalized linear mixed model with Bonferroni corrections; subject included as a random factor, and diet, day, and their interaction as fixed factors. Main effect of day (p < 0.001); incidence higher on HA days 1 and 18 relative to SL.

²Acute mountain sickness (AMS) was defined as a Lake Louise score >0.7 on the shortened version of the Environmental Symptoms Questionnaire (Beidleman et al., 2007).

³Incidence of nausea defined as slight to extreme nausea reported on the Environmental Symptoms Questionnaire.

^4–6Linear mixed model with Bonferroni corrections; subject included as a random factor, and diet, day, and their interaction as fixed factors. ⁴Diet-by-day interaction, p < 0.05. ^a–cValues within a dietary protein group sharing a superscript letter are not significantly different within that group. ⁵Main effect of group, p < 0.001. ⁶Main effect of day (p < 0.001); lower acceptability on HA days 1 and 18 relative to SL.

⁷Overall meal acceptability rated from 1 (dislike extremely) to 9 (like extremely). Values are the mean of ratings at breakfast, lunch, and dinner.

^*Significantly different from the same day in the standard-protein group, p < 0.05.