Fig. 3. Coupled configurational/conformational exploration of the junction between main and side chain around the connective center C9 through (a) a short range (τCP = 500 μs) DNP-enhanced 1H–13C LG-CP HETCOR spectrum revealing spatial contacts. (b) Structural model with black arrows indicating correlations observed within the rigid backbone, and red arrows indicating observed correlations between flexible parts. This analysis leads to two possible enantiomeric monomeric units with opposite absolute coupled configuration/conformation on the C9 center (c).
