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. 2018 Jun 15;29(12):1502–1517. doi: 10.1091/mbc.E17-09-0565

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© 2018 Diedrichs, Gomez, et al. “ASCB®,” “The American Society for Cell Biology®,” and “Molecular Biology of the Cell®” are registered trademarks of The American Society for Cell Biology.

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FIGURE 4: — Comparison of model and experimental outputs for deletion of ATF6α. (A–F) Selected model outputs are shown after ATF6α was deleted in silico (dashed lines), compared against outputs in wild-type simulations (solid lines). (G) Wild-type or Atf6–/– MEFs (two independent lines of each; genotype indicated above each panel) were treated with 5 nM TG for the indicated times, and expression of BiP and CHOP was assessed by immunoblot. See also Supplemental Figure S5. Loading control was a-actin. Hairlines are for visual clarity only.