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. 2018 Jun 14;9:1359. doi: 10.3389/fimmu.2018.01359

Figure 1.

Figure 1

Clinical protocols of MSC-treated kidney transplant recipients implemented at our center. The first two living-related donor kidney transplant recipients adopted the initial clinical protocol (Clinical protocol #1), where autologous bone marrow-derived MSC were infused 7 days after transplantation and induction therapy comprised basiliximab and low-dose RATG. Since in both patients transient acute renal insufficiency occurred due to engraftment syndrome, the protocol was revised (Clinical protocol #2), and two subsequent patients received pretransplant MSC infusion and induction therapy with low-dose RATG alone. Abbreviations: CsA, ciclosporin; MMF, mycophenolate mofetil; MSC, mesenchymal stromal cell; RATG, rabbit anti-thymocyte globulin.