TABLE 1:
Localization and depletion phenotypes of Tetrahymena condensin subunits.
| Localization | ||||
|---|---|---|---|---|
| Subunit | Gene ID | Germline | Soma | RNAi phenotype |
| Common condensins | ||||
| Smc2 | TTHERM_00812950 | * | * | Failure to segregate germline chromosomes in mitosis and meiosis, failure to divide somatic nucleus, somatic chromosomes cluster |
| Smc4 | TTHERM_00446400 | + | + | Not done |
| Cpg1 | TTHERM_00919690 | + | + | Not done |
| Cpdt1 | TTHERM_00486070 | + | + | Failure to segregate germline chromosomes in mitosis and meiosis, failure to divide somatic nucleus, somatic chromosomes cluster |
| Germline condensins | ||||
| Cph1 | TTHERM_00728870 | + | Anaphase bridging in mitosis and meiosis, partially redundant to Cph2 | |
| Cph2 | TTHERM_00540340 | + | Anaphase bridging in mitosis and meiosis, partially redundant to Cph1 | |
| Somatic condensins | ||||
| Cph3 | TTHERM_00554600 | * | Failure to divide somatic nucleus, somatic chromosomes cluster | |
| Cph4 | TTHERM_01299730 | + | None detected | |
| Cpdt2 | TTHERM_00392760 | + | Failure to complete sexual reproduction |
*Localization was inferred from the RNAi phenotype.