Fig. 2. Self-assembly process and architecture of respiratory chain supercomplexes. The time evolution of properties of the system with (+CL; blue) and without (-CL; cyan) cardiolipins are reported: (A) protein burial, ab, with contributions from the CIII/CIV and CIV/CIV interfaces, (B) numbers of interfaces, (C) numbers of CIII and CIV monomers, (D) the mean square displacement (MSD) of the CIII and CIV monomers in isolation in both membrane environments (+CL and -CL), and (E and F) average protein burial during CIII/CIV and CIV/CIV interface maturation with intra- and extra-membraneous contributions.
