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. 2016 Oct 23;39(1):67–76. doi: 10.1080/0886022X.2016.1244080

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© 2016 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/Licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 3. — (a) Photomicrograph of pancreas tissue section of control rats showing no histopathological alteration and the normal histological structure of the islands of Langerhans cells as endocrine portion as well as the acini and duct system as exocrine portion (H&Ex40). (b) Photomicrograph of pancreatic tissue section of diabetic rats showing atrophy in most of the islands of Langerhans cells with pyknosis of their nuclei and congestion in the blood vessels (H&Ex40). (c) Photomicrograph of pancreatic tissue section of diabetic nephroapathy rats showing edema with few inflammatory cells infiltration in the interlobular stroma (H&Ex40). (c1) It shows cystic dilatation in the ducts associated with congestion in the blood vessels (H&Ex40). (d, d1) Photomicrograph of pancreatic tissue section of diabetic rats treated with MSCs showing exocrine acini and fatty change in the lining epithelium with congestion in the blood vessels (H&Ex40). (e, e1) Photomicrograph of pancreatic tissue section of diabetic nephroapathy rats treated with MSCs showing no histopathological alteration in the islands of Langerhans cells, while the ducts showing periductal fibrosis.