Table 5.
Effect of MSCs infusion on serum advanced glycation end products (AGEs) level and heme oxygenase-1 (HO-1) activity in diabetic and diabetic nephropathy-bearing rats (mean ± SE).
| AGEs(ng/L) | HO-1(ng/L) | |
|---|---|---|
| Control | 208.25 ± 2.23 | 1541 ± 67.75 |
| Diabetic | 261.5 ± 6.7 | 1131.37 ± 13.8a |
| DN | 288.25 ± 9.18 | 1100.37 ± 19.65a |
| Diabetic + MSCs | 240 ± 12.95 | 1245.37 ± 16.36b |
| DN + MSCs | 222.12 ± 7.5 | 1283 ± 16.15b |
a
Significant change at p ≤ .05 in comparison with the control group.
b
Significant change at p ≤ .05 in comparison with diabetic-induced group.