Table 6.
Effect of MSCs infusion on serum growth factors (TGF-β, FGF-2, and PDGF) levels in diabetic and diabetic nephropathy-bearing rats (mean ± SE).
| TGF-β (ng/L) | FGF-2(ng/L) | PDGF(ng/L) | |
|---|---|---|---|
| Control | 30.51 ± 1.68 | 19.88 ± 2.799 | 1066.13 ± 22.52 |
| Diabetic | 47 ± 1.76a | 30.7 ± 0.494a | 1195.62 ± 2.013a |
| DN | 56.6 ± 1.91a | 36.27 ± 1.55a | 1253.83 ± 17.48a |
| Diabetic + MSCs | 35.93 ± 1.471b | 27.6 ± 0.863b | 1124.37 ± 13.4b |
| DN + MSCs | 36.16 ± 1.4b | 29.53 ± 0.872b | 1121.75 ± 22.38b |
a
Significant change at p ≤ .05 in comparison with the control group.
b
Significant change at p ≤ .05 in comparison with diabetic and diabetic nephropathy-induced groups.