Table 7.
Effect of MSCs infusion on iinterlukin-8 (IL-8) and monocyte chemoatractant-1(MCP-1) gene expression level in kidney tissue of diabetic and diabetic nephropathy-bearing rats (mean ± SE).
| IL-8 | MCP-1 | |
|---|---|---|
| Control | 0.368 ± 0.000598 | 0.287 ± 0.00197 |
| Diabetic | 1.055 ± 0.00451a | 0.097 ± 0.00491a |
| DN | 1.176 ± 0.00622a | 1.108 ± 0.00578a |
| Diabetic + MSCs | 0.719 ± 0.00228b | 0.48 ± 0.00427b |
| DN + MSCs | 0.324 ± 0.00416b | 0.348 ± 0.00311b |
a
Significant change at p ≤ .05 in comparison with the control group.
b
Significant change at p ≤ .05 in comparison with diabetic and diabetic nephropathy-induced groups.