Table 2.

Sensitivity, specificity, positive-predictive value, and negative-predictive value analyses for 1-year NRM

		Sensitivity	Specificity	PPV	NPV
Test cohort		0.70	0.74	0.55	0.85
Validation cohort 1		0.80	0.76	0.58	0.91
Validation cohort 2		0.63	0.93	0.58	0.91
Minnesota risk	Early treatment response
Standard	Response	0.50	0.86	0.29	0.94
Standard	Nonresponse	0.55	0.84	0.46	0.88
High*	Response	NA	NA	NA	NA
High	Nonresponse	0.94	0.54	0.84	0.78

NPV, negative-predictive value; PPV, positive-predictive value.

^*Too few patients with Minnesota high risk and early treatment response to calculate sensitivity, specificity, positive-predictive value, and negative-predictive value