Figure 1.

The CMTX3 complex insertion. Ideogram of chromosome 8 and chromosome X expanded to show (a) the region of chromosome 8q24.3 inserted into (b) the CMTX3 locus on chromosome X. Purple areas represent sequence contained within the CMTX3 locus. Orange areas represent the region of chromosome 8q23.4 inserted into the CMTX3 locus. Breakpoints are indicated by the vertical black broken lines. Letters A–D indicate sequences flanking the breakpoints. (c) Relative positions of the genes contained within the complex insertion and flanking the insertion site within the CMTX3 locus. Adapted from the gene track of UCSC Genome Browser (GRCh38/hg38) for the different genomic interval on chromosome Xq27.1 and chromosome 8q24.3