Figure 2.

The DHMN1 complex insertion. Ideogram of chromosome 7 expanded to show (a) the normal and (b) DHMNI locus. Blue areas represent sequence within the DHMN1 locus. Orange areas represent sequence at chromosome 7q36.3 inserted into the DHMN1 locus. The chromosome 7q36.3 sequence is located 2.3 Mb distal to the DHMN1 locus. Breakpoints are indicated by the vertical black broken lines. Letters A–G indicate sequences flanking the breakpoints. The sequence FG from chromosome 7q36.3 has been inserted into the DHMN1 locus in inverted orientation. (c) Relative positions of the genes contained within the complex insertion and flanking the insertion site within the DHMN1 locus. Adapted from gene tracks of the UCSC Genome Browser (GRCh38/hg38) for the specific chromosome 7q36.3 and 7q36.2 genomic intervals