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. 2017 Jan 24;39(1):340–349. doi: 10.1080/0886022X.2017.1279553

Table 2.

Serum and renal DPP-4 activity, renal GLP-1 level, and level of renal DPP-4 and GLP-1R mRNA.

	Sham	Vehicle	Alogliptin
Serum DPP-4 activity	0.082 ± 0.011	0.073 ± 0.016	0.063 ± 0.011
Renal DPP-4 activity	0.454 ± 0.023	0.236 ± 0.011^a	0.146 ± 0.003^a^,^b
Renal GLP-1 (pM)	13.39 ± 2.13	10.30 ± 2.905	21.21 ± 12.18
Relative DPP-4 mRNA (fold)	0.79 ± 0.27	3.46 ± 1.90	2.62 ± 0.96
Relative GLP-1R mRNA (fold)	1.37 ± 0.41	0.90 ± 0.21	0.74 ± 0.13

Data are shown as mean ± SE.

^a

p< 0.01 compared with the sham-operated group.

^b

p< 0.01 compared with the vehicle-treated group.