Table 1.
Baseline and transplant characteristics of patients with Alport syndrome compared to patients with end-stage kidney disease (ESKD) from other causes.
Variables | Non-Alport renal disease N = 3856 | Alport syndrome N = 62 | p values |
---|---|---|---|
Age at transplant, mean (sd) | 41.9 (16.3) | 33.31 (12.65) | <0.001 |
Age at ESKD, mean (sd) | 39.7 (16.0) | 30.7 (12.3) | <0.001 |
Sex, % male/female | 63.6/36.4 | 83.9/16.1 | 0.001 |
Time on transplant waiting pool in months, median (IQR) | 13.1 (6.2–24.6) | 12.9 (4.4–22.4) | 0.515 |
Cold ischemic time in hours, median (IQR) | 19 (16–22) | 20 (17–23) | 0.232 |
HLA mismatches, median (IQR) | 3 (2–4) | 3 (2–4) | 0.372 |
Transplant number, % first transplants | 86.0 | 80.6 | 0.232 |
Living donor transplants, % | 7.4 | 14.5 | 0.034 |
Pre-emptive transplants, % | 6.0 | 1.6 | 0.146 |
PRA groups,% 0–10, 11–49, 50–100 | 62.8/18.0/19.2 | 76.7/6.7/16.7 | 0.045 |