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. 2018 May 1;41(7):1501–1509. doi: 10.2337/dc17-1896

Table 3.

Tests of differences in slopes of neurocognitive function by age splines and MetS status

Δ SE P value
B-SEVLT-sum
 Slope differences age <65 −0.012 0.004 0.0066
 Slope differences age ≥65 0.038 0.020 0.0561
 No MetS: slope differences age <65 vs. age ≥65 0.055 0.016 0.001
 MetS: slope differences age <65 vs. age ≥65 0.005 0.013 0.711
B-SEVLT-recall
 Slope differences age <65 −0.013 0.004 0.0027
 Slope differences age ≥65 0.024 0.020 0.2291
 No MetS: slope differences age <65 vs. age ≥65 0.031 0.016 0.053
 MetS: slope differences age <65 vs. age ≥65 −0.007 0.014 0.62
WF
 Slope differences age <65 −0.001 0.005 0.7519
 Slope differences age ≥65 −0.017 0.025 0.5041
 No MetS: slope differences age <65 vs. age ≥65 0.001 0.021 0.97
 MetS: slope differences age <65 vs. age ≥65 0.016 0.016 0.307
DSS
 Slope differences age <65 −0.004 0.004 0.2787
 Slope differences age ≥65 0.014 0.017 0.3929
 No MetS: slope differences age <65 vs. age ≥65 0.001 0.014 0.968
 MetS: slope differences age <65 vs. age ≥65 −0.018 0.010 0.069
Global cognition
 Slope differences age <65 −0.013 0.004 0.0036
 Slope differences age ≥65 0.035 0.020 0.0722
 No MetS: slope differences age <65 vs. age ≥65 0.047 0.016 0.003
 MetS: slope differences age <65 vs. age ≥65 −0.001 0.014 0.926
Low mental status
 Slope differences age <65 −0.002 0.018 0.9017
 Slope differences age ≥65 −0.161 0.078 0.0383
 No MetS: slope differences age <65 vs. age ≥65 −0.152 0.068 0.025
 MetS: slope differences age <65 vs. age ≥65 0.007 0.040 0.854
Age <65 vs. age ≥65 (age65*MetS interaction)
B-SEVLT-sum 0.0204
B-SEVLT-recall 0.0162
WF 0.7379
DSS 0.1223
Global cognition 0.0409
Low mental status 0.8723

Estimates based on survey-generalized linear regression models assuming a Gaussian distribution for continuous outcomes (Z scores) and logistic distribution for low mental status. MetS was defined using the IDF specifications. Models include sex, age splines (at age 65)*MetS interaction, education, Hispanic/Latino background, and CES-D-10 scale.