Table 4.
Association of individual MetS components and components count with neurocognitive function among Hispanics/Latinos of diverse backgrounds
| β (SE) |
OR (95% CI) |
|||||
|---|---|---|---|---|---|---|
| B-SEVLT-sum | B-SEVLT-recall | WF | DSS | Global cognition | Low mental status | |
| Component 1 | ||||||
| Abdominal obesity | 0.45 (0.232) | 0.33 (0.216) | −0.01 (0.033) | 0.05 (0.028) | 0.4 (0.212) | 0.9 (0.72; 1.12) |
| Age | −0.02 (0.003)*** | −0.02 (0.003)*** | −0.00 (0.002)** | −0.03 (0.001)*** | −0.02 (0.003)*** | 1.05 (1.04; 1.06)*** |
| Obesity*age | −0.01 (0.004) | −0.01 (0.004) | NA | NA | −0.01 (0.004) | NA |
| Component 2 | ||||||
| TGs | 0.06 (0.165) | 0.37 (0.160)* | −0.04 (0.024) | −0.05 (0.021)* | 0.14 (0.154) | 0.93 (0.77; 1.11) |
| Age | −0.02 (0.002)*** | −0.02 (0.002)*** | −0.00 (0.002)** | −0.03 (0.001)*** | −0.02 (0.002)*** | 1.05 (1.04; 1.06)*** |
| TGs*age | −0.002 (0.003) | −0.01 (0.003)* | NA | NA | −0.003 (0.003) | NA |
| Component 3 | ||||||
| HDL cholesterol | −0.08 (0.152) | 0.14 (0.156) | −0.07 (0.027)** | −0.06 (0.020)** | −0.04 (0.145) | 1.03 (0.87; 1.23) |
| Age | −0.02 (0.002)*** | −0.02 (0.002)*** | −0.00 (0.002)** | −0.03 (0.001)*** | −0.03 (0.002)*** | 1.05 (1.04; 1.06)*** |
| HDL*age | 0.001 (0.003) | −0.002 (0.003) | NA | NA | 0.00 (0.003) | NA |
| Component 4 | ||||||
| Elevated BP | 0.34 (0.161)* | 0.06 (0.152) | −0.09 (0.026)*** | −0.06 (0.021)** | 0.24 (0.150) | 1.08 (0.89; 1.31) |
| Age | −0.02 (0.003)*** | −0.02 (0.002)*** | 0 (0.002) | −0.03 (0.001)*** | −0.02 (0.002)*** | 1.05 (1.04; 1.06)*** |
| Elevated BP*age | −0.01 (0.003)* | −0.002 (0.003) | NA | NA | −0.01 (0.003) | NA |
| Component 5 | ||||||
| IFG | 0.53 (0.164)** | 0.42 (0.159)** | −0.07 (0.029)* | −0.06 (0.020)** | 0.47 (0.156)** | 1.12 (0.92; 1.36) |
| Age | −0.02 (0.002)*** | −0.02 (0.002)*** | −0.00 (0.002)* | −0.03 (0.001)*** | −0.02 (0.002)*** | 1.05 (1.04; 1.06)*** |
| IFG*age | −0.01 (0.003)*** | −0.01 (0.003)** | NA | NA | −0.01 (0.003)** | NA |
| Sum components | ||||||
| Sum | 0.16 (0.058)** | 0.17 (0.058)** | −0.04 (0.010)*** | −0.03 (0.008)*** | 0.15 (0.055)** | 1.01 (0.95; 1.08) |
| Age | −0.01 (0.003)*** | −0.01 (0.003)*** | −0.00 (0.002)* | −0.03 (0.001)*** | −0.02 (0.003)*** | 1.05 (1.04; 1.06)*** |
| Sum*age | −0.003 (0.001)** | −0.003 (0.001)** | NA | NA | −0.003 (0.001)** | NA |
| MetS | ||||||
| MetS | 0.53 (0.153)*** | 0.58 (0.149)*** | −0.09 (0.029)** | −0.09 (0.021)*** | 0.50 (0.144)*** | 1.07 (0.90; 1.29) |
| Age | −0.02 (0.002)*** | −0.02 (0.002)*** | −0.00 (0.002)* | −0.03 (0.001)*** | −0.02 (0.002)*** | 1.05 (1.04; 1.06)*** |
| MetS*age | −0.01 (0.003)*** | −0.01 (0.003)*** | NA | NA | −0.01 (0.003)*** | NA |
Estimates based on survey-generalized linear regression models assuming a Gaussian distribution for continuous outcomes (Z scores) and logistic distribution for low mental status. MetS and its components are defined using IDF specifications. Models adjust for age, sex, education, Hispanic/Latino background, and CES-D-10 scale. IFG, impaired fasting glucose; NA, interaction not included in the model.
*P < 0.05;
**P < 0.01;
***P < 0.001.