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. 2018 May 3;67(7):1297–1309. doi: 10.2337/db17-1509

Figure 5.

Figure 5

Increased β-oxidation and inflammation in HFD-fed Pik3r1 R649W mice. A: Liver triglycerides measured after 8 weeks of CD or HFD. B: Representative images from liver sections stained with hematoxylin and eosin. Results are shown as mean ± SEM. *P < 0.05, one-way ANOVA. mRNA expression of genes involved in de novo lipogenesis (C), fatty acid oxidation (D), β-oxidation (E), gluconeogenesis (F), and inflammation (G) in livers from WT and KI animals after 8 weeks of the CD or HFD. mRNA results are mean ± SEM of 5–6 animals per group. *P < 0.05 compared with controls, t tests.