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Presence of Pik3r1 R649W mutation in ob/ob mice does not change mRNA expression of regulators of lipid metabolism. mRNA expression of genes involved in lipid metabolism (A), adipocyte development (B), and inflammation (C) in the subcutaneous (top panel) and epididymal (bottom panel) fat in ob/ob and ob/ob-KI mice at 8 weeks of age. mRNA results are mean ± SEM of 4–6 animals per group. *P < 0.05, **P < 0.01, ***P < 0.001 compared with controls, t tests.
