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. Author manuscript; available in PMC: 2019 May 1.
Published in final edited form as: Cytotherapy. 2018 Apr 11;20(5):728–739. doi: 10.1016/j.jcyt.2018.03.001

Figure 3. Global gene expression analysis of HER2/neu DCs manufactured with healthy donor monocytes using patient and healthy donor AB plasma.

Figure 3

Monocytes from 3 different healthy subjects were used to manufacture HER2/neu DCs using plasma from patient #13 which was associated with poor HER2/neu expression when used to manufacture autologous DCs (Auto). AdHER2/neu DCs were also manufactured with the same healthy donor monocytes and heathy donor AB plasma (AB) and an equal mixture of patient #13 and AB plasma (Mix). The 9 DCs were analyzed by global gene expression analysis. A total of 2085 genes were differentially expressed among the DCs manufactured with patient #13 and AB plasma. The 9 DCs were subjected to hierarchical clustering analysis using the 2085 differentially expressed genes.