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. 2018 Jun 22;13(6):e0199378. doi: 10.1371/journal.pone.0199378

Table 3. Multivariable linear regression of HbA1c levels.

All
Variables β 95% CI p-value
Age (years) -0.009 -0.014 to -0.003 0.002
Male vs. female 0.029 -0.116 to 0.174 0.693
CVD 0.030 -0.113 to 0.173 0.680
BMI (kg/m2) 0.002 -0.015 to 0.020 0.795
MAP (mmHg) -0.002 -0.007 to 0.003 0.421
eGFR (ml/min/1.73 m2) 0.012 0.005 to 0.018 <0.001
Log UPCR 0.308 0.146 to 0.469 <0.001
Albumin (g/dl) -0.210 -0.343 to -0.077 0.002
Hemoglobin (g/dl)
 In total population 0.099 0.058 to 0.141 <0.001
 In Hb ≥ 10 g/dl* 0.014 -0.054 to 0.082 0.689
 In Hb < 10 g/dl* 0.146 0.047 to 0.245 0.004
Log cholesterol 2.098 1.524 to 2.672 <0.001
Log CRP 0.059 -0.011 to 0.130 0.097
Phosphate (mg/dl) -0.063 -0.133 to 0.006 0.072

Abbreviations: Hb, hemoglobin; CVD, cardiovascular disease; BMI, body mass index; MAP, mean arterial pressure; eGFR, estimated glomerular filtration rate; UPCR, urine protein-to-creatinine ratio; CRP, C-reactive protein.

* Segmental linear regression with the same variables

P < 0.05 indicates a significant association with HbA1c levels.