Table 4. Risk of outcomes among subjects with Hb < 10 g/dL and Hb ≥ 10 g/dL, stratified by HbA1c quartiles.

	All				Hemoglobin < 10 g/dl				Hemoglobin ≥ 10 g/dl
	HbA1c quartiles				HbA1c quartiles				HbA1c quartiles
	Q1	Q2	Q3	Q4	Q1	Q2	Q3	Q4	Q1	Q2	Q3	Q4
HR (95% CI) for RRT
Unadjusted	1	0.68 (0.46–1.00)*	1.13 (0.81–1.58)	1.28 (0.93–1.77)	1	0.80 (0.47–1.34)	1.12 (0.69–1.79)	0.59 (0.35–1.00)	1	0.69 (0.38–1.23)	1.42 (0.88–2.30)	2.25 (1.44–3.54)*
Adjusted a	1	1.05 (0.71–1.57)	1.37 (0.96–1.93)	1.34 (0.95–1.87)	1	1.24 (0.71–2.17)	1.32 (0.80–2.20)	0.79 (0.45–1.36)	1	1.14 (0.62–2.10)	1.65 (0.99–2.76)	1.92 (1.17–3.15)*
HR (95% CI) for all-cause mortality
Unadjusted	1	1.43 (0.98–2.11)	1.23 (0.83–1.81)	1.51 (1.04–2.19)*	1	1.51 (0.88–2.60)	1.07 (0.59–1.94)	0.96 (0.53–1.71)	1	1.69 (0.96–2.96)	1.68 (0.97–2.91)	2.34 (1.38–3.96)*
Adjusted a	1	1.79 (1.21–2.65)*	1.30 (0.87–1.93)	1.49 (1.01–2.18)*	1	1.62 (0.92–2.85)	0.94 (0.50–1.76)	1.04 (0.56–1.91)	1	2.17 (1.23–3.84)*	1.72 (0.98–3.02)	1.76 (1.02–3.03)*
HR (95% CI) for CV event + all-cause mortality
Unadjusted	1	0.96 (0.70–1.33)	1.07 (0.78–1.45)	1.45 (1.08–1.95)*	1	1.13 (0.70–1.81)	1.05 (0.65–1.69)	0.89 (0.55–1.44)	1	1.01 (0.65–1.58)	1.27 (0.84–1.93)	2.07 (1.40–3.06)*
Adjusted a	1	1.26 (0.91–1.76)	1.28 (0.93–1.75)	1.40 (1.03–1.89)*	1	1.20 (0.73–1.97)	1.05 (0.64–1.73)	1.01 (0.61–1.67)	1	1.29 (0.82–2.03)	1.51 (0.98–2.32)	1.54 (1.03–2.31)*

^a The Cox proportional hazard model was adjusted for age, sex, estimated glomerular filtration rate, log (urine protein-to-creatinine ratio), cardiovascular disease, hypertension, mean blood pressure, hemoglobin, albumin, log (cholesterol), log (C-reactive protein), phosphorus, body mass index and iron.

Abbreviations: RRT, renal replacement therapy

* p < 0.05 indicates significant differences compared with the reference group