Table 1. Sample collection schedule for index cases and contacts (n = 142) among enrolled households in Managua, Nicaragua, August to October, 2016.
| Visit 01 | Visit 12 Day 1 |
Visit 2 Days 3/4 |
Visit 3 Days 6/7 |
Visit 4 Days 9/10 |
Visit 5 Day 21 |
|
|---|---|---|---|---|---|---|
| Index cases (n = 33) | ||||||
| Blood | X | X3 | X3 | |||
| Urine | X | X | X | X | X | X |
| Saliva | X | X | X | X | X | X |
| Contacts (n = 109) | ||||||
| Blood | X | X | X | |||
| Urine | X | X | X | X | X | |
| Saliva | X | X | X | X | X | |
1Applies only to index cases: 28 from PDCS and 5 from national surveillance (n = 33). No urine or saliva samples were available for surveillance cases.
2Enrollment day for index cases and contacts.
3For the 28 index cases that were PDCS participants [32], the second and final visits correspond to a plasma sample, whereas all the other collected blood samples are serum. The 5 surveillance index cases only have an enrollment (visit 1) and final (visit 5) serum sample available.