Associations of reproducible molecular features with baseline total water arsenic and baseline total urinary arsenic. (A) A Venn diagram shows the overlap of the metabolites that had a significant association with water arsenic, urinary arsenic, and urinary MMA%. (B) Heatmap of multivariable Pearson correlations of baseline total water arsenic and urinary arsenic with the reproducible metabolites that were nominally significantly associated with water arsenic or urinary arsenic. The coefficients were adjusted for sex, age, and cohort memberships. Note: MMA%, percent monomethylarsonic acid.