Table 3.
Menstruating (n = 118) | Amenorrhea (n = 104) | Difference | |||||
---|---|---|---|---|---|---|---|
| |||||||
Symptom | Score | SE | Score | SE | Beta | SE | Adjusted p |
General | |||||||
Overall low energy/fatigue* | 0.75 | 0.21 | 1.29 | 0.19 | 0.55 | 0.24 | 0.03 |
Cough | 0.21 | 0.09 | 0.27 | 0.08 | 0.06 | 0.10 | 0.54 |
Fever/night sweats/chills | 0.14 | 0.12 | 0.24 | 0.11 | 0.10 | 0.14 | 0.45 |
Shortness of breath with activity | 0.37 | 0.15 | 0.30 | 0.14 | −0.06 | 0.16 | 0.70 |
Gastrointestinal | |||||||
Nausea/vomiting | 0.18 | 0.14 | 0.23 | 0.12 | 0.04 | 0.15 | 0.78 |
Diarrhea | 0.40 | 0.16 | 0.38 | 0.15 | −0.02 | 0.18 | 0.93 |
Constipation/gas/bloating | 0.47 | 0.16 | 0.49 | 0.14 | 0.03 | 0.18 | 0.88 |
Heartburn/reflux | 0.28 | 0.12 | 0.29 | 0.11 | 0.01 | 0.14 | 0.96 |
Thirst/dry mouth | 0.34 | 0.15 | 0.30 | 0.13 | −0.05 | 0.17 | 0.77 |
Changes in appetite | 0.17 | 0.14 | 0.26 | 0.13 | 0.10 | 0.16 | 0.52 |
Unplanned weight loss/gain | 0.12 | 0.14 | 0.38 | 0.13 | 0.25 | 0.16 | 0.10 |
Pain | |||||||
Muscle aches/joint pain* | 0.99 | 0.23 | 1.47 | 0.21 | 0.48 | 0.25 | 0.05 |
Neurological | |||||||
Lightheadedness/dizziness | 0.39 | 0.14 | 0.29 | 0.12 | −0.10 | 0.16 | 0.53 |
Neuropathy (numbness or tingling in hands/feet) | 0.77 | 0.19 | 0.81 | 0.17 | 0.04 | 0.21 | 0.84 |
Ringing in ears/noise intolerance | 0.17 | 0.11 | 0.30 | 0.10 | 0.14 | 0.12 | 0.26 |
Clumsy walking/balance difficulty/dropping things frequently | 0.39 | 0.13 | 0.25 | 0.11 | −0.14 | 0.14 | 0.31 |
Cognitive | |||||||
Speech difficulties (e.g. slowed speech, reversing numbers, words) | 0.13 | 0.10 | 0.11 | 0.09 | −0.01 | 0.11 | 0.94 |
Difficulty concentrating/easily distracted | 0.17 | 0.17 | 0.47 | 0.15 | 0.31 | 0.18 | 0.10 |
Difficulty remembering things | 0.32 | 0.18 | 0.55 | 0.16 | 0.24 | 0.20 | 0.23 |
Sleep | |||||||
Difficulty falling asleep* | 0.66 | 0.24 | 1.22 | 0.21 | 0.56 | 0.27 | 0.04 |
Difficulty staying asleep | 0.65 | 0.22 | 0.99 | 0.19 | 0.35 | 0.25 | 0.17 |
Mood/Emotions | |||||||
Anxiety or fear (e.g. feeling nervous) | 0.65 | 0.22 | 0.84 | 0.19 | 0.19 | 0.25 | 0.44 |
Depression (e.g. feeling worthless, hopeless) | 0.78 | 0.24 | 1.15 | 0.21 | 0.35 | 0.27 | 0.19 |
Eyes/Vision | |||||||
Dry eyes | 0.15 | 0.14 | 0.35 | 0.13 | 0.20 | 0.16 | 0.21 |
Urogenital | |||||||
Difficulty with urination | 0.18 | 0.10 | 0.21 | 0.09 | 0.03 | 0.10 | 0.77 |
Pain or discomfort during sex | 0.02 | 0.08 | 0.06 | 0.08 | 0.04 | 0.10 | 0.67 |
Decreased sex drive | 0.12 | 0.15 | 0.30 | 0.13 | 0.18 | 0.17 | 0.28 |
symptom #26, erectile dysfunction, removed from the follow-up female survey;
= significant p value = ≤ 0.05 for linear mixed model; Beta= regression coefficient, SE = standard error