Table 3.

Association analysis of bacterial localization with bacterial density of samples and with clinical profiles of patients.

Bacterial localization profiles	Number of samples	Number (median) of bacterial genome copies		Mean of probing pocket depth (mm)	Mean age	Sex (male/female)
		PG	TF
Total	82	117	441	6.7	58	31/51
Extracellular
PG and TF	55	440*a	1098*b	6.9	59*i	20/35
TF only	15	0*a	124*b	6.4	60	8/7
both negative	12	0	3	5.8	49*i	3/9
Intracellular
In inflammatory cells
PG and TF	18	722*c	2074	7.2	58	8/10
TF only	21	256*c	773	6.9	63	6/15
both negative	43	4	101	6.3	55	17/26
In squamous epithelium
PG and TF	12	722	2040	6.8	64	5/7
TF only	5	890	4627	6.2	62	1/4
both negative	65	41	444	6.7	56	25/40
In capillary endothelium
PG and TF	4	2273	4984	7.0	64	2/2
TF only	4	23	8419	7.0	60	1/3
both negative	74	117	369	6.6	57	28/46
Extracellular PG and
PG in inflammatory cells
positive	18	722*d	2074	7.2	58	8/10
negative	37	327*d	880	6.7	59	12/25
PG in epithelium
positive	12	722	2040	6.8	64	5/7
negative	43	359	998	6.9	57	15/28
PG in endothelium
positive	4	2273	4984	7.0	64	2/2
negative	51	440	1098	6.9	58	18/33
Extracellular TF and
TF in inflammatory cells
positive	39	391*e	1738*g	7.1	60	14/25
negative	31	74*e	267*g	6.5	57	14/17
TF in epithelium
positive	17	774*f	2236*h	6.6	63	6/11
negative	53	88*f	531*h	6.9	58	22/31
TF in endothelium
positive	8	159	2500	7.0	62	3/5
negative	62	243	827	6.8	59	25/37

*^aP < 0.0001, *^bP = 0.0009, *^cP = 0.0094, *^dP = 0.037, *^eP = 0.013, *^fP = 0.0031.

*^gP = 0.0010, *^hP = 0.0021, *ⁱP = 0.0095.