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. 2018 Jun 22;8:9554. doi: 10.1038/s41598-018-27900-5

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Essentiality analysis of expanded Htt co-IP proteins specific proteins. The bar-plot shows the percentage of essential genes of each group in S. cerevisiae (blue) and S. pombe (yellow). The Y-axis indicates the percentage of essential genes, and the X-axis shows the name of each group. Dashed lines show the background percentage of essential genes in the genome of S. cerevisiae (blue) and S. pombe (yellow). Asterisk shows the statistical significance in each group (*P < 0.05, **P < 0.01), calculated by the Fisher’s exact test. Detailed values and statistical results are provided in Supplementary Table 2.