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. 2018 Jun 22;8:9498. doi: 10.1038/s41598-018-27883-3

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Effect of lesion laterality: bilateral analysis of the associations between lesions in different supratentorial regions and 3-month outcomes. (a) Lesion overlays of patients with or without poor functional outcome and death in the merged C1 + C2 cohort. (b) Results of VLSM analysis: z-score maps revealing significant associations with death and poor functional outcome before and after VC in the merged C1 + C2 cohort. (c) Number of voxels in each anatomical region associated with death and poor functional outcome before and after VC in the merged C1 + C2 cohort: the associations mostly affect left brain regions. Abbreviations: VC, volume control; SLF, superior longitudinal fasciculus; IFOF, inferior fronto-occipital fasciculus; UF, uncinate fasciculus; CT, corticospinal tract.