Table 1.

General characteristic of patients in both cohorts.

	COHORT 1			P	COHORT 2			P
	All patients (n = 90)	Insula+ (n = 57)	Insula− (n = 33)		All patients (n = 105)	Insula+ (n = 74)	Insula− (n = 31)
Age (years), mean (SD)	73 (12)	74 (13)	71 (12)	0.248	69 (12)	68 (12)	71 (11)	0.252
Sex (male), %	63	60	70	0.340	51	51	52	0.980
Admission NIHSS score, median (IQR)	10 (4–17)	14 (9–20)	4 (2–8)	<0.001	17 (12–20)	17 (12–20)	12 (10–18)	0.017
Glucose at admission,	138 (56)	131 (41)	149 (75)	0.162	128 (39)	129 (43)	126 (29)	0.754
Large vessel occlusion, %	83	89	71	0.005	96	97	94	0.580
Acute revascularization, %				0.339				0.273
None	15	12	18		5	3	10
IV only	62	60	67		24	26	19
IA (±IV)	23	28	15		71	71	71
24 h NIHSS score, median (IQR)	5 (2–15)	9 (4–19)	2 (0–3)	<0.001	8 (3–16)	10 (5–17)	4 (1–12)	0.001
Infarct volume (cc), median (IQR)	18 (3–53)	28 (17–82)	2 (1–6)	<0.001	15 (5–53)	25 (11–82)	3 (0.2–10)	<0.001
Laterality (right/left), %	48/52	53/47	41/59	0.277	48/52	50/50	42/58	0.450
Etiologic stroke subtype, %				0.017				0.022
Cardioembolic	43	51	29		50	53	36
Large vessel atherosclerosis	19	14	29		18	16	24
Lacunar	6	0	17		0	0	7
Undetermined etiology	27	28	25		23	25	24
Other	5	7	0		9	6	9
3-month mRS score, median (IQR)	2 (1–4)	2 (1–4)	1 (0–2)	<0.001	3 (1–4)	3 (2–5)	1 (0–2)	0.135
Death at 3 months, %	12	18	3	0.050	11	15	3	0.105
Cause of death				0.231				0.007
Cerebrovascular	55	60	0		50	55	0
Cardiovascular	18	20	0		17	18	0
Infection	0	0	0		25	27	0
Unknown	27	20	100		8	0	100

Abbreviations: NIHSS, National Institutes of Health Stroke Scale; mRS, modified Rankin Scale.