Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Jun 22;9:2435. doi: 10.1038/s41467-018-04848-8

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 5 — Uterine glands are essential for decidual progression and pregnancy establishment in mice. Control, gland-containing Ltf^iCre/+Foxa2^f/f and glandless Pgr^Cre/+Foxa2^f/f mice received i.p. injections of recombinant mouse LIF on GD 4 and were evaluated on GDs 6, 7, and 8. a Sections of implantation sites were stained with hematoxylin and eosin. Note the variation in embryo and decidua development on GDs 7 and 8 in the glandless Pgr^Cre/+Foxa2^f/f uterus. Row 1—Scale bar: 250 μm; Row 2—Scale bar: 150 μm; Row 3—Scale bar: 150 μm. b Immunofluorescence analysis of PTGS2 and Ki67 (cell proliferation marker) in implantation sites on GD 6. Scale bar: 100 μm. c Immunofluorescence analysis of PTGS2 and Ki67 (cell proliferation marker) in implantation sites on GD 7. Scale bar: 250 μm. d Gross morphology of the uterus on GD 8 (top panel). White arrowheads indicate individual implantation sites. Scale bar: 1 cm. TUNEL staining to detect apoptosis in implantation sites on GD 8 (bottom panel). Scale bar: 250 μm. Em: embryo, Dec: decidua, Pdz: primary decidual zone, Sdz: secondary decidual zone. All images are representative of three independent experiments