3.
两组患者不良反应比较
Comparison of toxicities between two groups
| Toxicities | G-T group (n=49) | T-G group (n=56) | P* | P↑ | |||||||
| Ⅰ | Ⅱ | Ⅲ | Ⅳ | Ⅰ | Ⅱ | Ⅲ | Ⅳ | ||||
| P*: Test including all grades; P↑: test comparing grade >Ⅲ and grade < Ⅱ. | |||||||||||
| Leukopenia | 3 (6.12%) |
8 (16.33%) |
4 (8.16%) |
17 (34.69%) |
8 (14.29%) |
8 (14.29%) |
7 (12.50%) |
10 (17.86%) |
0.252 | 0.184 | |
| Granulocytopenia | 4 (8.16%) |
12 (24.49%) |
7 (14.29%) |
9 (18.37%) |
4 (7.14%) |
6 (10.71%) |
5 (8.93%) |
9 (16.07%) |
0.166 | 0.386 | |
| Lower hemoglobin | 5 (10.20%) |
9 (18.37%) |
4 (8.16%) |
13 (26.53%) |
14 (25.00%) |
13 (23.21%) |
5 (8.93%) |
4 (7.14%) |
0.049 | 0.027 | |
| Thrombocytopenia | 2 (4.08%) |
2 (4.08%) |
3 (6.12%) |
13 (26.53%) |
3 (5.36%) |
3 (5.36%) |
3 (5.36%) |
2 (3.57%) |
0.021 | 0.002 | |
| Gastrointestinal reaction | 10 (20.41%) |
10 (20.41%) |
2 (4.08%) |
0 (0) | 9 (16.07%) |
8 (14.29%) |
0 (0) | 1 (1.79%) |
0.321 | 0.597 | |
| Renal dysfunction | 16 (32.65%) |
2 (4.08%) |
0 (0) | 0 (0) | 14 (25.00%) |
5 (8.93%) |
0 (0) | 0 (0) | 0.475 | — | |
| Hepatic dysfunction | 13 (26.53%) |
2 (4.08%) |
0 (0) | 0 (0) | 6 (10.71%) |
3 (5.36%) |
0 (0) | 0 (0) | 0.110 | — | |