Table 1.
Gene names of ESCRTs from the organisms discussed in this review. Aliases, typically used in mammalian systems, are provided. Fly and worm orthologues compiled from Flybase beta (FB2017_93) and Wormbase WS259. Where orthologues were predicted, but not annotated, sequence identifiers were used. Usp-50 and Ego-2’s equivalence to UBPY and PTPN23 was from [180].
| S. cerevisiae | H. sapiens | C. elegans | D. melanogaster | Aliases | |
|---|---|---|---|---|---|
| ESCRT-0 | Vps27 | HGS | hgrs-1 | Hrs | HRS |
| Hse1 | STAM1/STAM2 | stam-1 | Stam | ||
| ESCRT-I | Vps23 | TSG101 | tsg-101 | Tsg101 | |
| Vps28 | VPS28 | vps-28 | Vps28 | ||
| Vps37 | VPS37A/VPS37B/VPS37C/VPS37D | vps-37 | Vsp37a/Vps37b | ||
| Mvb12 | UBAP/MVB12A/MVB12B | mvb-12 | Mvb12 | ||
| ESCRT-II | Vps25 | VPS25 | vps-25 | Vps25 | EAP20 |
| Vps22 | VPS22 | vps-22 | Vps22/Larsen (Lsn) | EAP30 | |
| Vps36 | VPS36 | vps-36 | Vps36 | EAP45 | |
| ESCRT-III | Did2/Vps46 | CHMP1A/CHMP1B | did-2 | Chmp1 | |
| Vps2 | CHMP2A/CHMP2B | vps-2 | Chmp2b | ||
| Vps24 | CHMP3 | vps-24 | Vps24 | ||
| Snf7 | CHMP4A/CHMP4B/CHMP4C | vps-32 | shrub | ||
| Vps60 | CHMP5 | vps-60 | Vps60 | ||
| Vps20 | CHMP6 | vps-20 | Vps20 | ||
| Chm7 | CHMP7 | T24B8.2 | CG5498 | ||
| Ist1 | IST1 | istr-1 | CG10103 | ||
| ESCRT | Bro1 | PDCD6IP/PTPN23 | alx-1/ego-2 | ALiX | ALIX/HD-PTP |
| Associated | Doa4 | UBPY/STAMBP | usp-50 | Usp8/CG2224 | UBPY/AMSH |
| Vta1 | VTA1 | T23G11.7 | Vta1 | LIP5 | |
| Vps4 | VPS4A/VPS4B | vps-4 | Vps4 | SKD1 (VPS4B) | |
| SPAST | spas-1 | Spastin | Spastin | ||
| CC2D1A/CC2D1B | Y37H9A.3 | Lethal (2) Giant Discs (Lgd) | |||
| MITD1 | Y66D12A.10 | CG14985 | |||