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. 2018 Apr 20;7(9):e007802. doi: 10.1161/JAHA.117.007802

Figure 9.

Figure 9

Schematic representation of a combined regulatory network for the expression of the cardiac sodium channel gene SCN5A. RNA binding protein, Hu Antigen R (HuR), is associated with myocyte enhancer factor‐2C (MEF2C) mRNA, and the association protects MEF2C mRNA from degradation. The elevated MEF2C transcriptionally enhances SCN5A mRNA expression. SCN5A indicates sodium channel α‐subunit; CDS, coding sequences; UTR, untranslated region.