Table 4.
Univariable and Multivariable Analyses of LVD and RVD in PPCM Outcomes
| Outcomes | |
|---|---|
| No. of participants | 53 |
| Follow‐up time, median (IQR), y | 3.6 (1.4–7.3) |
| No. of events | 17 |
| Event rate, per 100 person‐years (95% CI) | 65.6 (40.7–100.5) |
| Model | HR | 95% CI | P Value |
|---|---|---|---|
| Univariable models | |||
| Moderate‐severe RVD | 4.26 | 1.57–11.6 | 0.005 |
| LVEF <30% | 4.85 | 1.11–21.3 | 0.036 |
| LVEDD ≥60 mm | 2.45 | 0.79–7.5 | 0.117 |
| MR severity | |||
| None | 1 | NA | NA |
| Mild | 0.97 | 0.19–5.0 | 0.970 |
| Moderate | 1.94 | 0.39–9.7 | 0.420 |
| Severe | 3.80 | 0.66–22 | 0.137 |
| Multivariable model 1 | |||
| Moderate‐severe RVD | 3.21 | 1.13–9.10 | 0.028 |
| LVEF <30% | 2.17 | 0.37–12.8 | 0.391 |
| LVEDD ≥60 mm | 1.41 | 0.38–5.25 | 0.607 |
| Multivariable model 2 | |||
| Moderate‐severe RVD | 3.18 | 1.12–9.08 | 0.030 |
| LVEF <30% | 3.21 | 0.69–14.9 | 0.137 |
| Multivariable model 3 | |||
| Moderate‐severe RVD | 3.59 | 1.30–9.92 | 0.014 |
| LVEDD ≥60 mm | 1.99 | 0.64–6.18 | 0.235 |
| Multivariable model 4 | |||
| Moderate‐severe RVD | 4.79 | 1.45–16 | 0.010 |
| MR severity | |||
| None | 1 | NA | NA |
| Mild | 0.41 | 0.06–2.6 | 0.348 |
| Moderate | 1.01 | 0.17–6.0 | 0.995 |
| Severe | 1.22 | 0.16–9.32 | 0.848 |
CI indicates confidence interval; HR, hazard ratio; IQR, interquartile range; LVD, left ventricular dysfunction; LVEDD, left ventricular end‐diastolic diameter; LVEF, left ventricular ejection fraction; MR, mitral regurgitation; NA, not applicable; PPCM, peripartum cardiomyopathy; RVD, right ventricular dysfunction.