Table 4.

Association Between Exposure (Any HPD or Preeclampsia Specifically) With Future AF (Per Woman), With and Without Adjusting for Hypertension^a and BMI >30^b

Factor	Model 1 Unadjusted		Model 2 Adjusted for Hypertension		Model 3 Adjusted for BMI		Model 4 Adjusted for Both
	OR (95% CI)	P Valuec	Adjusted OR (95% CI)	P Valuec	Adjusted OR (95% CI)	P Valuec	Adjusted OR (95% CI)	P Valuec
Any HPDd	2.60 (1.21–6.04)	0.011	2.07 (0.92–4.96)	0.068	2.40 (1.08–5.78)	0.021	2.12 (0.92–5.23)	0.061
Hypertensiona	···	···	1.82 (0.96–3.53)	0.054	···	···	1.41 (0.72–2.83)	0.34
BMI >30b	···	···	···	···	5.48 (1.56–9.50)	0.003	4.60 (1.25–25.59)	0.013
Preeclampsiae	1.83 (0.62–6.04)	0.33	1.33 (0.42–4.57)	0.62	1.46 (0.47–4.98)	0.61	1.20 (0.37–4.21)	0.80
Hypertensiona	···	···	2.08 (1.12–4.00)	0.016	···	···	1.64 (0.85–3.25)	0.13
BMI >30b	···	···	···	···	5.67 (1.64–30.18)	0.002	4.42 (1.22–24.29)	0.014

AF indicates atrial fibrillation; BMI, body mass index; CI, confidence interval; HPD, hypertensive pregnancy disorder; OR, odds ratio.

^aHypertension at the time of index date.

^bBMI >30 at any first prenatal visit.

^cExact P value derived from score statistic from fitting a conditional logistic regression model.

^dThe prevalence of HPD was 26.7% (28/105) and 11.4% (12/105) among AF cases and controls, respectively.

^eThe prevalence of preeclampsia was 10.5% (11/105) and 5.7% (6/105) among AF cases and controls, respectively.