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TCaM alleviated ventricular tachycardia in vivo in CPVT mice R33Q. A, Representative surface ECG traces from WT mice, R33Q mice or R33Q mice treated with TCaM. B, Average of VT incidence, n=8 to 19, *P<0.05 vs R33Q, #P<0.05 vs WT. C, Percentage of survival after ECG n=8 to 19, *P<0.05 vs R33Q, #P<0.05 vs WT. CPVT indicates catecholaminergic polymorphic ventricular tachycardia; ECG, electrocardiogram; TCaM, therapeutic calmodulin; VT, ventricular tachycardia.
