Table 2.

Patients With Pilsicainide‐Induced Ventricular Arrhythmia

Patients	Age (y)	Sex	Spontaneous Type 1	Clinical Presentation	FH of SD	VF Induction by PES	SCN5A Mutation	Type of SCB‐VTA	ICD Implantation During Follow‐Up	VTA During Follow‐Up
1	50	Male	Yes	Asymptomatic	Yes	Yes	No	Frequent PVC	No	Sustained VT
2	27	Male	Yes	Asymptomatic	No	Yes	No	Frequent PVC	No	None
3	55	Male	Yes	Syncope	No	Yes	No	VF	Yes	Appropriate ICD shock
4	41	Male	Yes	VF	No	Yes	No	NSVT	Yes	Appropriate ICD shock
5	55	Male	Yes	VF	Yes	Yes	No	Frequent PVC	Yes	Appropriate ICD shock
6	42	Male	No	VF	No	Yes	No	Frequent PVC	Yes	None
7	41	Male	Yes	Syncope	No	No	No	NSVTa	Yes	None
8	57	Male	Yes	Asymptomatic	No	No	No	Frequent PVC	No	None
9	47	Male	Yes	Syncope	Yes	No	Yes	Frequent PVC	Yes	Appropriate ICD shock
10	29	Male	Yes	Syncope	Yes	No	Yes	Sustained VTa	No	None
11	40	Male	Yes	Asymptomatic	Yes	Yes	No	NSVT	Yes	None
12	50	Male	Yes	Syncope	No	Yes	No	VF	Yes	Appropriate ICD shock
13	42	Male	Yes	Asymptomatic	No	Yes	No	Frequent PVC	Yes	Appropriate ICD shock
14	38	Male	Yes	Asymptomatic	Yes	Yes	No	Frequent PVC	No	None
15	34	Male	Yes	Syncope	Yes	Yes	No	Frequent PVC	Yes	Appropriate ICD shock
16	38	Male	Yes	Syncope	No	No	Yes	NSVT	No	None
17	50	Male	Yes	Asymptomatic	No	Yes	NA	NSVTa	Yes	None
18	27	Male	Yes	Asymptomatic	Yes	Yes	No	NSVT	No	SD
19	50	Male	Yes	Syncope	No	Yes	NA	Sustained VT	No	VF
20	36	Male	Yes	Syncope	Yes	Yes	No	NSVT	Yes	None
21	74	Male	Yes	Asymptomatic	Yes	Yes	NA	Frequent PVC	Yes	Sustained VT
22	36	Male	Yes	Asymptomatic	No	Yes	NA	Frequent PVC	Yes	Appropriate ICD shock
23	25	Male	Yes	Syncope	No	No	Yes	VTa/VF	Yes	Appropriate ICD shock
24	41	Male	Yes	Asymptomatic	No	Yes	NA	Frequent PVC	No	None

FH indicates family history; ICD, implantable cardioverter defibrillator; NA, not assessed; NSVT, nonsustained ventricular tachycardia; PES, programmed electrical stimulation; PVC, premature ventricular contraction; SCB, sodium channel blocker; SD, sudden death; VF, ventricular fibrillation; VT, ventricular tachycardia; VTA, ventricular tachyarrhythmia.

^aVT with wide QRS complex and not significant polymorphic change.