Table 1.
Baseline Characteristics and Echocardiographic Parameters in Experimental Groups
| Control Group (n=10) | DM Group (n=10) | ALLO Group (n=10) | |
|---|---|---|---|
| Weight, kg | 2.56±0.21 | 2.59±0.28 | 2.79±0.30 |
| Glucose level at 8 wks, mmol/L | 5.55±0.27 | 16.15±8.27a | 11.63±5.84a |
| HR, bpm | 176.40±15.46 | 168.40±10.83 | 164.40±15.13 |
| SBP, mm Hg | 86.71±14.34 | 96.43±11.27 | 110.71±29.05 |
| DBP, mm Hg | 69.86±15.93 | 65.14±31.77 | 91.57±36.66 |
| LVEDP, mm Hg | 8.04±3.33 | 2.84±2.54 | 3.88±3.24 |
| LAD, mm | 7.26±0.57 | 8.57±0.95 | 7.85±1.27 |
| Septal wall thickness, mm | 1.71±0.13 | 2.08±0.23a | 1.91±0.19 |
| Posterior wall thickness, mm | 1.65±0.15 | 2.07±0.35a | 1.90±0.20 |
| LV end diastolic diameter, mm | 12.42±0.84 | 14.38±1.00a | 13.55±1.30 |
| LV end systolic diameter, mm | 6.82±0.52 | 8.61±1.47a | 8.06±1.09 |
| LV ejection fraction, % | 70.23±7.81 | 76.25±11.54 | 69.57±11.88 |
| E, cm/s | 55.62±9.03 | 66.68±7.94 | 50.08±14.95b |
| A, cm/s | 41.17±13.67 | 38.40±9.12 | 39.18±12.93 |
| E/A | 1.38±0.27 | 1.85±0.68 | 1.37±0.53 |
| Heart weight ratio, 1/1000 | 2.18±0.69 | 2.39±0.18a | 2.24±0.25 |
| Atrium weight ratio, 1/1000 | 0.26±0.08 | 0.31±0.02a | 0.29±0.03 |
| LV weight ratio, 1/1000 | 1.51±0.93 | 1.74±0.15a | 1.61±0.13 |
Values are mean±SD. ALLO indicates allopurinol; DBP, aortic diastolic blood pressure; HR, heart rate; IVST, interventricular septal wall thickness; LAD, left atrial anteroposterior diameter; LV, left ventricular; LVEDP, left ventricular end‐diastolic pressure; LVEF,left ventricular ejection fraction; SBP, aortic systolic blood pressure.
a
Compared with the control group P<0.05.
b
Compared with the DM group P<0.05.