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. 2018 Jun 1;7(11):e007451. doi: 10.1161/JAHA.117.007451

Figure 1.

Figure 1

Premature mortality, hypertrophy, and diastolic dysfunction with preserved systolic function in the hypertrophic heart rat (end point age 50 weeks, prefailure 30 weeks). A, Survival, normal heart rat (NHR, dashed line) and hypertrophic heart rat (HHR, solid line). B, Postmortem cardiac weight index (mg/g). (50 weeks). C, Exemplar M‐mode echocardiographs HHR vs NHR hearts, and exemplar blood flow and tissue Doppler images (50 weeks). D, Preserved systolic function in HHR with minimal decrement of ejection fraction (EF). E, Left ventricular internal diameter (diastole) (LVIDd). F, Diastolic function—E/E′. G, Heart rate (HR, bpm). Graphs show mean ± SEM. For A, *P=0.0004 (log‐rank Mantel‐Cox test), for B and D through G, *P<0.05 (Student t test, n=6–10 hearts/group).