Table 4.

Multivariable‐Adjusted Logistic Regression Analyses for EHRA Score and EHRA Symptom Dimensions Separately in Relation to Interventions to Restore Sinus Rhythm at 1 Year

Variable	Odds Ratio for EHRA 3/4 Versus 1/2	95% Confidence Interval	P Value	P Value (Adjusted Logistic Regression Across All 4 Categories)
Cardioversion, N=701 (11.3%)
Palpitations	1.32	1.08 to 1.61	0.0073	<0.0001
Fatigue	1.16	0.97 to 1.39	0.11	0.18
Dizziness	1.27	0.98 to 1.64	0.07	0.32
Dyspnea	1.05	0.86 to 1.27	0.65	0.79
Chest pain	1.37	0.97 to 1.93	0.08	0.20
Anxiety	0.79	0.63 to 0.99	0.042	0.08
EHRA score	1.21	1.01 to 1.45	0.040	0.07
Catheter‐based ablation, N=226 (3.4%)
Palpitations	2.02	1.48 to 2.76	<0.0001	<0.0001
Fatigue	1.67	1.23 to 2.26	0.0009	0.0017
Dizziness	1.11	0.70 to 1.75	0.65	0.90
Dyspnea	1.19	0.84 to 1.68	0.26	0.008
Chest pain	1.41	0.79 to 2.52	0.24	0.25
Anxiety	1.26	0.88 to 1.80	0.21	0.20
EHRA score	1.97	1.44 to 2.69	<0.0001	<0.0001
Sinus rhythm at 1 y, N=2022 (32.6%)
Palpitations	1.51	1.30 to 1.76	<0.0001	<0.0001
Fatigue	0.98	0.86 to 1.12	0.76	0.93
Dizziness	0.90	0.74 to 1.10	0.31	0.75
Dyspnea	0.86	0.74 to 0.99	0.033	0.003
Chest pain	1.44	1.90 to 1.10	0.0085	0.012
Anxiety	1.04	0.89 to 1.22	0.60	0.007
EHRA score	1.06	0.93 to 1.20	0.40	0.048
Adequate heart rate control, N=2734 (44.1%)
Palpitations	0.81	0.68 to 0.95	0.012	0.031
Fatigue	0.86	0.74 to 0.99	0.036	0.03
Dizziness	1.004	0.82 to 1.23	0.97	0.23
Dyspnea	0.88	0.76 to 1.02	0.10	0.16
Chest pain	0.84	0.62 to 1.14	0.27	0.51
Anxiety	0.91	0.76 to 1.07	0.25	0.51
EHRA score	0.80	0.70 to 0.92	0.0015	0.005

Odds ratios are provided for EHRA score category 3/4 vs 1/2. P values across all 4 categories are from logistic regression analyses, as implemented in SAS proc logistic. All models are adjusted for age, sex, country, body mass index, systolic blood pressure, hypertension, diabetes mellitus, smoking, heart failure, and history of myocardial infarction. EHRA indicates European Heart Rhythm Association.