Table 5.

Unadjusted and Propensity‐Matched Association Between All MRA Use and Outcomes

Outcome	Unadjusted		Propensity‐Matched
	HR or OR (95% CI)	P Value	HR or OR (95% CI)	P Value
AF progressiona	1.36 (1.10–1.67)	0.0047	1.11 (0.92–1.34)	0.2685
All‐cause death	1.86 (1.45–2.39)	<0.0001	1.07 (0.84–1.37)	0.5791
Cardiovascular death	2.64 (1.81–3.84)	<0.0001	1.29 (0.90–1.84)	0.1614
First stroke, non‐CNS embolism, or TIA	0.75 (0.44–1.31)	0.3146	0.60 (0.31–1.16)	0.1300
New‐onset HF	2.82 (1.46–5.46)	0.0020	2.40 (1.19–4.88)	0.0150
First cardiovascular hospitalization	1.42 (1.18–1.71)	0.0002	1.00 (0.86–1.18)	0.9551

AF indicates atrial fibrillation; CI, confidence interval; CNS, central nervous system; HF, heart failure; HR, hazard ratio; MRA, mineralocorticoid antagonist; TIA, transient ischemic attack.

^aOdds ratio (OR) reported.