Table 3.

Correlations Between Biomarkers and Diastolic Function Indexes at Baseline in the RELAX Cohort

	Spearman Correlation Coefficients P Values Number of Observations
	LA Volume Index	E/A Ratio	Medial E/e′ (m/sec)	Lateral E/e′ (m/sec)	Relative Wall Thickness	LV Mass
PTX3	0.41	0.18	0.02	−0.16	0.08	0.26
	0.002	0.196	0.872	0.165	0.523	0.042
	57	53	73	73	60	60
IL‐6	0.11	−0.11	0.18	0.22	0.23	0.05
	0.438	0.434	0.134	0.066	0.084	0.691
	57	52	72	72	60	60
TNF‐α	0.06	−0.31	0.17	0.15	0.14	0.16
	0.672	0.040	0.176	0.238	0.305	0.244
	52	46	65	65	54	54
hs‐CRP	−0.12	−0.10	0.07	0.07	0.10	0.00
	0.400	0.468	0.567	0.569	0.435	0.987
	55	52	71	71	59	59

hs‐CRP indicates high sensitivity C reactive protein; IL‐6, interleukin 6; LA, left atrial; LV, left ventricular; PTX3, pentraxin 3; RELAX, Effect of Phosphodiesterase‐5 Inhibition on Exercise Capacity and Clinical Status in Heart Failure with Preserved Ejection Fraction; TNF‐A, tumor necrosis factor‐α.