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. 2018 Apr 5;7(8):e008150. doi: 10.1161/JAHA.117.008150

Table 3.

Number of Events, Crude and Adjusted Event Rates Among 4 Treatment Groups

Apixaban (n=5843) Dabigatran (n=20 079) Rivaroxaban (n=27 777) Warfarin (n=19 375)
Events Crude Incidencea Adjusted Incidenceb Events Crude Incidencea Adjusted Incidenceb Events Crude Incidencea Adjusted Incidenceb Events Crude Incidencea Adjusted Incidenceb
Ischemic stroke/systemic embolism 100 2.26 2.26 854 2.74 2.90 977 2.84 3.00 929 3.26 3.55
Ischemic stroke 91 2.06 2.06 747 2.40 2.56 870 2.53 2.65 793 2.79 3.05
Acute myocardial infarction 23 0.52 0.52 134 0.43 0.47 146 0.42 0.43 177 0.62 0.61
All‐cause mortality 319 7.22 7.22 1575 5.05 6.69 2051 5.97 6.57 2588 9.09 10.96
Intracranial hemorrhage 31 0.70 0.70 233 0.75 0.70 272 0.79 0.74 378 1.33 1.41
Major gastrointestinal bleeding 28 0.63 0.63 362 1.16 1.28 394 1.15 1.07 444 1.56 1.65
All major bleeding 67 1.52 1.52 625 2.01 2.12 707 2.06 1.97 855 3.00 3.25
a

Events divided by 100 person‐years.

b

Inverse probability of treatment weighted to apixaban and expressed as population average treatment rates per 100 years.