Table 2.
Intracellular cytokines—cell prevalence data
| % of parent population | Moderate HIE (n = 17) |
Severe HIE (n = 11) |
NAIS (n = 4) |
|
|---|---|---|---|---|
| IL-10+ CD8+ / CD8+ | 6 h | 2.75 (1.19–4.12) | 4.19 (1.94–6.91) | 1.10 (0.40–1.36) b, p = 0.01 |
| IL-10+ CD4+ / CD4+ | 24 h | 2.88 (1.56–7.03) | 4.52 (3.02–6.59) | 9.47 (5.10–20.68) a, p = 0.03 |
| IL-10+ CD8+ / CD8+ | 72 h | 3.51 (1.85–5.12) | 5.30 (2.41–6.08) | 1.39 (0.52–2.99) b, p = 0.03 |
| TGF-β + CD49d + CD4+ / CD4+ | 1 week | 10.54 (4.77–14.28) | 10.0 (5.46–15.20) | 38.00 (14.93–46.78) a, p = 0.03; b, p = 0.05 |
| TGF-β + CD4+ / CD4+ | 1 month | 3.51 (1.46–4.47) | 3.54 (2.47–6.27) | 1.30 (0.54–2.49) b, p = 0.05 |
| IL-17+ CD8+ / CD8+ | 6 h | 3.89 (5.26–14.40) | 2.30 (1.73–4.49) c, p = 0.02 |
5.04 (4.62–7.68) b, p = 0.03 |
| IFN-γ + CD4+ / CD4+ | 72 h | 6.40 (3.70–11.80) | 6.17 (4.75–13.01) | 17.50 (2.74–30.20) |
| IL-6+ CD8+ /CD8+ | 72 h | 4.37 (3.26–6.29) | 5.63 (2.68–8.80) | 8.87 (4.75–10.52) |
| IL-6+ CD8+ /CD8+ | 1 month | 4.02 (2.40–10.74) | 3.70 (2.31–6.16) | 4.47 (2.88–8.33) |
The prevalence of T cells expressing various cytokines are shown as the percentage of the parent population