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. 2018 Jun 20;6:e5109. doi: 10.7717/peerj.5109

Table 2. Risk factors.

No. of event Observed person-years ID Crude HR 95% C.I. Adjusted HR 95% CI
Lower Upper Lower Upper
Chronic periodontitis
 No 483 651,552 0.7 1 1
 Yes 869 655,566 1.3 1.79** 1.60 2.00 1.79** 1.60 2.00
Age
 <20 53 135,583 0.4 1 1
 20–39 339 518,847 0.7 1.67** 1.25 2.23 1.56** 1.16 2.10
 40–64 747 549,571 1.4 3.48** 2.63 4.60 2.82** 2.11 3.78
 ≧65 213 103,117 2.1 5.28** 3.91 7.14 3.67** 2.66 5.05
Gender
 Male 352 615,103 0.6 1 1
 Female 1,000 692,015 1.4 2.52** 2.24 2.85 2.55** 2.25 2.88
Monthly income
 <NT $20,000 677 639,530 1.1 1 1
 NT $20,000–NT $40,000 384 359,006 1.1 1.01 0.89 1.15 0.94 0.82 1.07
 >NT $40,000 291 308,582 0.9 0.89 0.78 1.02 1.02 0.88 1.18
Urbanization
 Urban 903 879,933 1.0 1 1
 Suburban 381 354,024 1.1 1.05 0.93 1.18 1.07 0.94 1.20
 Rural 68 73,161 0.9 0.91 0.71 1.16 0.86 0.67 1.11
Hypertension 266 149,842 1.8 1.89** 1.65 2.16 0.99 0.84 1.15
Hyperlipidemia 176 86,980 2.0 2.10** 1.79 2.46 1.24* 1.04 1.47
Chronic insomnia 634 304,042 2.1 2.91** 2.62 3.24 2.08** 1.86 2.32
CCI
 0 839 999,322 0.8 1 1
 1 421 256,471 1.6 1.95** 1.74 2.20 1.38** 1.21 1.56
 ≧2 92 51,325 1.8 2.14** 1.72 2.65 1.30* 1.03 1.62

Notes:

Risk factor analysis of primary Sjögren’s syndrome development.

Charlson comorbidity index; ID: Incidence density, per 1,000 person-years.

Adjusted for age, gender, monthly income, urbanization, hypertension, hyperlipidemia, chronic insomnia, and Charlson comorbidity index.

*

p < 0.05.

**

p < 0.01.